Dr. Olujide Olubiyi

Research Scientist 

Academic and Professional Qualifications

 

  • 2000: BPharm, Pharmacy (Distinction) - Obafemi Awolowo University, Ile-Ife, Nigeria 

  • 2009: MSc Drug Discovery (Distinction) - School of Pharmacy, University College London 

  • 2013: PhD Drug design (Sehr gut) - RWTH University Aachen, Germany

 

Career History

  • 2014 - Present: Senior Lecturer, Department of Pharmacology and Therapeutics, College of Medicine & Health Sciences, Afe Babalola University, Ado-Ekiti, Nigeria

 

  • 04/2013 -11/2013: Postdoctoral Research Fellowship, Institute of Complex Systems 6, Forschungszentrum Jülich, Germany

 

  • 06/2011: Visiting scientist, Prof Paul Axelsen’s research laboratory. University of Pennsylvania, Philadelphia, United State of America

 

  • 11/2010 - 01/2011: Guest Researcher, Institute of Structural Biochemistry, Forschungszentrum Jülich, Germany

Research Interests

  • Molecular basis of drug action

  • Drug discovery and structure-based drug design

  • Mechanism of drug-receptor interactions and computer-aided drug design

  • Ethnopharmacology and drug repurposing

 

 

 

Brief Profile

Olujide Olubiyi currently holds a faculty position at the Department of Pharmacology and Therapeutics, College of Medicine and Health Sciences of the Afe Babalola University, Ado-Ekiti. His research interest includes molecular mechanism of the biological actions of small compounds, structure-based and computer-aided drug design, medicinal chemistry, and the structural basis of allosteric inhibition. Olujide received a bachelor of pharmacy degree from the Faculty of Pharmacy, Obafemi Awolowo University, Ile-Ife in 2006 after which he proceeded to two federal tertiary hospitals where he gained clinical experience in the use of drugs. In 2008 he was awarded the Commonwealth Scholarships  to undertake a Master in Drug Discovery degree from the London School of Pharmacy, now School of Pharmacy, University College London. On completing his master education in the United Kingdom he  proceeded to Germany for a doctoral training in Alzheimer's disease drug design, awarded  by the RWTH Aachen. He would later do a postdoctoral research work at the Forschungszentrum Julich, Germany in 2013

 

Selected Publications

 

  • Conformational polymorphism in the autophagy-related protein GATE-16. Ma P, Schillinger O, Hartmann R, Stoldt M, Mohrlüder J, Schwarten M, Olubiyi O, Strodel B, Willbold D, and Weiergräber OH. Biochemistry, 2015. {in press}

 

  • Early Amyloid Β-Protein Aggregation Precedes Conformational Change. Barz B, Olubiyi OO and Strodel B. Chemical  Communications, 2014.

 

  • Amyloid Aggregation Inhibitory Mechanism of Arginine-Rich D-Peptides. Olubiyi OO , Frenzel D, Bartnik D, Glück JM, Brener O, Nagel-Steger L, Funke SA, Willbold D, Strodel B. Current Medicinal Chemistry, 2014

 

  • A Predictive Model for Ethnomedicinal Discovery Research- A Nigerian Case Study. Olubiyi OO and Akintayo CO. Journal of Biomedical and Pharmaceutical Research, 3, 6, 1-8, 2014.

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  • Determination of Binding Affinities of Some Approved Drugs to Ascaris suum Mitochondrial Rhodoquinol-Fumarate Reductase By in silico Molecular Docking. Uzochukwu IC, Olubiyi OO, Akpojotor CO. Journal of Pharmaceutical and Allied Sciences, 2014.

 

  • Presented paper: Introduction to drug discovery and computer-aided drug design. Workshop on molecular docking and drug design. 4th July 2014, NAFDAC Laboratories/Faculty of Pharmacy, Nnamdi Azikwe University Agulu, Anambra State.

 

  • Presented paper: Molecular dynamics simulation-From Newton’s classical mechanics to pharmacological mechanisms. Workshop on molecular docking and drug design. 4th July 2014, NAFDAC Laboratories/Faculty of Pharmacy, Nnamdi Azikwe University Agulu, Anambra State.

 

  • Presented paper: ­Setting up molecular dynamics simulations for test pharmological systems. Workshop on molecular docking and drug design. 4th July 2014, NAFDAC Laboratories/Faculty of Pharmacy, Nnamdi Azikwe University Agulu, Anambra State.

 

  • Structures of the Amyloid β-Peptides Aβ(1-40) and Aβ (1-42) as Influenced by pH and a D-Peptide. Olubiyi OO and Strodel B. Journal of Physical Chemistry B, 116, 3280-3291, 2012.

 

  • Molecular Dynamics of HIV1-Integrase in Complex with 93del – A Structural Perspective on the Mechanism of Inhibition.Sgobba M, Olubiyi OO, Ke S, Haider S. Journal of Biomolecular Structure and Dynamics. 29:863-877, 2012.

 

  • Molecular Modeling of Human Alkaline Sphingomyelinase. Suresh PS, Olubiyi O, Thirunavukkarasu C, Strodel B, Kumar MS. Bioinformation, 6, 78-82, 2011.

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  • Book Chapter: From Computational Biophysics to Systems Biology (CBSB11). Olubiyi OO and Strodel B. Jülich,Germany. ISBN 978-3-89336-748-1. 2012

 

  • Book: Investigation of the interaction between Alzheimer’s abeta peptide and aggregation inhibitors using molecular simulations. Olubiyi OO. RWTH Aachen University, Germany. 2013 (Published doctoral thesis available online).

     

 

Contact Details:

Emails: o.olujide@breacnigeria.org; jideolubiyi@gmail.com

Tel: +2347032508107

 

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